ISO/TS TECHNICAL SPECIFICATION 16489 First edition 2006-05-15 Water quality Guidance for establishing the equivalency of results Qualite de I'eau Lignes directrices pour la création de I'équivalence des résultats Reference number ISO/TS 16489:2006(E) @ISO2006 ISO/TS 16489:2006(E) PDFdisclaimer This PDF file may contain embedded typefaces. In accordance with Adobe's licensing policy, this file may be printed or viewed but accepts no liability in this area. Adobe is a trademark of Adobe Systems Incorporated. Details of the software products used to create this PDF file can be found in the General Info relative to the file; the PDF-creation parameters were optimized for printing. Every care has been taken to ensure that the file is suitable for use by IsO member bodies. In the unlikely event that a problem relating to it is found, please inform the Central Secretariat at the address given below. ?ISO2006 All rights reserved. Unless otherwise specified, no part of this publication may be reproduced or utilized in any form or by any means, ISsO's member body in the country of the requester. ISO copyright office Case postale 56. CH-1211 Geneva 20 Tel. + 41 22 749 01 11 Fax + 41 22 749 09 47 E-mail [email protected] Web www.iso.org Published in Switzerland ii @ ISO 2006 -All rights reserved ISO/TS 16489:2006(E) Contents Page Foreword. IV Introductior 1 Scope 2 Normative references 3 Terms and definitions 4 Overview of the different approaches. 5 Amount of data. 6 Data comparisons.. 7 Comparison of arithmetic means of two independently obtained sets of data ... 8 Comparison of population and sample arithmetic means 9 Analysis of variance 10 Determination of the equivalence of analytical results obtained from samples from different matrices ... 10.1 General..... 10.2 Determination of the equivalence of the analytical results of real samples using orthogonal regression. 10.3 Evaluation according to the difference method.. 11 Reporting .. .10 Annex A (informative) Statistical tables.. .11 Annex B (informative) Example of a comparison of arithmetic means of two independently obtained sets of data... .13 Annex C (informative) Example of a comparison of population and sample arithmetic means.. ..15 Annex D (informative) Example of an analysis of variance . ...16 Annex E (informative) Examples of a comparison of results from samples of different matrices.... ......18 Annex F (informative) Illustrative examples of graphic plots .24 Annex G (informative) Schematic diagrams 21 Bibliography.. 29 @ ISO 2006 - All rights reserved ii ISO/TS 16489:2006(E) Foreword IsO (the International Organization for Standardization) is a worldwide federation of national standards bodies technicalcommittees.Eachmemberbodyinterestedinasubjectforwhichatechnicalcommitteehasbeer established has the right to be represented on that committee. International organizations, governmental and non-governmental, in liaison with isO, also take part in the work. iso collaborates closely with the International Standards are drafted in accordance with the rules given in the ISO/lEC Directives, Part 2. The main task of technical committees is to prepare International Standards. Draft International Standards adopted by the technical committees are circulated to the member bodies for voting. Publication as an International Standard requires approval by at least 75 % of the member bodies casting a vote. technical committee may decide to publish other types of normative document: an ISO Publicly Available Specification (ISO/PAS) represents an agreement between technical experts in an isO working group and is accepted for publication if it is approved by more than 50 % of the members of the parent committee casting a vote; committee and is accepted for publication if it is approved by 2/3 of the members of the committee casting a vote. An ISO/PAS or ISO/TS is reviewed after three years in order to decide whether it will be confirmed for a further three years, revised to become an Int